A split night study is recommended for an AHI of ____ or more during at least ___ hours of baseline recording, with at least ______ hours of time remaining for titration.

The correct answer is based on the recommendations for conducting a split-night polysomnography study, which is often used to assess patients with obstructive sleep apnea (OSA).

For a split-night study to be warranted, an apnea-hypopnea index (AHI) of 40 or more is indicative of severe OSA. This threshold is established to ensure that the patient has a level of sleep-disordered breathing that is significant enough to warrant immediate intervention, which is why the AHI of 40 or more is considered during the baseline recording phase.

Additionally, the study protocol emphasizes the necessity of observing at least 2 hours of baseline recording. This duration allows for sufficient data gathering on the patient's typical sleep architecture and patterns, ultimately leading to more accurate titration of therapeutic pressure.

Moreover, there needs to be time allocated for titration; in this case, having at least 3 hours remaining is essential. This period is critical as it allows the sleep technologist or physician to implement and adjust treatment effectively after confirming that the patient is experiencing severe obstructive events.

Thus, the values of 40 for AHI, 2 hours for baseline recording, and 3 hours for titration collectively form a guideline that ensures the study’s efficacy in